Arteriosclerosis

Experimental Arteriosclerosis

Arteriosclerotic lesions have been produced in monkeys (Macaca nemestrina) by selective removal of the vascular endothelium with an intra-arterial balloon catheter. Immediately after de-endothelialization a platelet layer covers the denuded area. This thrombus is gradually removed and by 7 days the vessel appears to be largely reendothelialized. Beginning at day 4, smooth muscle cells undergo m...

Spontaneous Arteriosclerosis in Rabbits

Cerebral arteriosclerosis.

Arteriosclerosis in Parkinsonism.

Some textbooks on general and neurological medicine give the impression that cerebral arteriosclerosis is an important cause of Parkinsonism (e.g., Alpers, 1945; Yater, 1949; Purves-Stewart and Worster-Drought, 1952; Wilson, 1955; Cecil and Loeb, 1959; Grinker, Bucy, and Sahs, 1959; Merritt, 1959; Baker, 1962; Brain, 1962). Whether or not this is so, it is often very difficult to distinguish cl...

Arteriosclerosis: facts and fancy.

Arterial vascular diseases comprise the leading cause of death in the industrialized world. Every physician learns about the pathology of these diseases in medical school. All pathologists evaluate arterial disease in surgical pathology and/or autopsy specimens. All clinicians encounter patients with clinical manifestations of these diseases. With such a common and clinically-important group of...